MAximising Therapeutic Utility in Rheumatoid Arthritis
The MRC-MATURA TranSMART is a web-based knowledge management platform that enables MATURA consortium members to develop and refine research hypotheses by investigating correlations between genetic, genomic and phenotypic data, and assessing their analytical results in the context of published literature and other work related to RA disease pathology and drug response.
The MRC-MATURA TranSMART infrastructure enables integrated analysis towards the identification of biomarker signatures that will help researchers and clinicians better understand the different responses to biologic drugs that are seen in the clinic, ultimately offering better and more personalised treatment to those affected by rheumatoid arthritis.
The MRC-MATURA TranSMART platform enables researchers to:
The TranSMART community
The TranSMART platform, which was originally developed and open sourced by our industrial partner, Janssen, is now widely used internationally for translational research (http://transmartfoundation.org/). The MRC-MATURA TranSMART has itself been developed in close collaboration with the MRC-PSORT and the MRC-RA-MAP consortium in collaboration with the Innovative Medicines Initiative (IMI) project European Translational Information and Knowledge Management Services (eTRIKS).